Description

19-Deoxy-6-Hydroxychetocin is a structurally complex natural product derivative belonging to the epipolythiodioxopiperazine class. This compound is of significant interest in biochemical and pharmaceutical research due to its potential as a potent and selective inhibitor of histone methyltransferases. It serves as a critical research tool for scientists in the fields of epigenetics, oncology, and molecular biology, enabling the study of gene regulation and cellular differentiation pathways.

Application

• Epigenetics Research: As a potent inhibitor of histone methyltransferases, it is used to study chromatin remodeling, gene silencing, and transcriptional regulation.
• Oncology and Cancer Biology: Investigated for its role in modulating oncogenic pathways and its potential as a lead compound for novel anti-cancer therapeutics.
• Biochemical Pathway Analysis: A key reagent for probing specific enzymatic activity and understanding the function of methyltransferase enzymes in cellular processes.
• Pharmaceutical R&D: Utilized in high-throughput screening and structure-activity relationship (SAR) studies for drug discovery programs targeting epigenetic modifiers.
• Academic Research: Employed in university and institutional labs for fundamental studies in cell differentiation, stem cell biology, and developmental processes.

Basic Information

Product Name	19-Deoxy-6-Hydroxychetocin
CAS No.	12794-85-3
Molecular Formula	C30H30N6O8S2
Molecular Weight	666.72 g/mol
Synonyms	19-Deoxy-6-hydroxychetocin; Chetocin derivative; Epipolythiodioxopiperazine derivative; Histone methyltransferase inhibitor; HMT inhibitor; ETP derivative; 6-Hydroxy-19-deoxychetocin; Research compound 12794-85-3
EINECS	Contact for details

Quality Control

Our 19-Deoxy-6-Hydroxychetocin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a dry, cool, and well-ventilated area. Allow the product to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.