Description

Glucagon, Hydrochloride is a high-purity peptide hormone essential for regulating blood glucose levels. Its primary commercial value lies in its critical role as an active pharmaceutical ingredient (API) for emergency hypoglycemia treatment. This product is indispensable for pharmaceutical manufacturers, research institutions, and diagnostic kit producers requiring a reliable and well-characterized biological agent. Consistent quality and supply chain integrity are paramount for its end-use in life-saving medications and advanced metabolic research.

Application

• Pharmaceutical API: Core active ingredient in injectable emergency kits for severe hypoglycemia (low blood sugar).
• Diagnostic Reagent: Used in clinical diagnostic tests and kits to assess pancreatic function and glycogen storage diseases.
• Biochemical Research: Vital tool for studying glucose metabolism, liver function, hormone signaling pathways, and diabetes mechanisms.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in laboratories.
• Veterinary Medicine: Application in veterinary settings for managing hypoglycemia in companion animals.
• Cell Culture & Biotechnology: Used in specific bioprocessing and cell culture applications to modulate metabolic activity.

Basic Information

Product Name	Glucagon, Hydrochloride
CAS No.	11140-85-5
Molecular Formula	C153H225N43O49S • xHCl
Molecular Weight	~3483 (as free base)
Synonyms	Glucagon HCl; Glucagon Hydrochloride; Glukagon; HGF; Hyperglycemic Glycogenolytic Factor; 1H-Glucagon; Glucagon (human); Glucagon recombinant; Glucagon acetate (salt); Glucagon-like peptide 1
EINECS	Contact for details

Quality Control

Our Glucagon, Hydrochloride is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity and related substances, potency (biological activity) assays, and tests for residual solvents and endotoxins. We support compliance with cGMP guidelines for pharmaceutical ingredients. A detailed Certificate of Analysis (COA) providing full specification results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or under refrigeration at 2-8°C as specified. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to standard
Assay (HPLC)	≥ 97.0%
Biological Potency	95% - 105% of stated potency
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 10.0%
Acetate Content (HPLC)	≤ 15.0% (if applicable)
Endotoxins	< 10.0 EU/mg
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.