Description

Holothurin B is a bioactive triterpene glycoside, a key saponin compound derived from marine sea cucumbers. This high-purity reference standard is essential for pharmaceutical research, particularly in the development of novel anti-cancer and anti-inflammatory therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies for pharmacological studies, bioactivity screening, and as a critical analytical standard.

Application

• Pharmaceutical Research & Development: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in the investigation of new anti-tumor and cytotoxic agents.
• Cancer Research: Used in in vitro and in vivo studies to evaluate its efficacy against various cancer cell lines due to its potent cytotoxic properties.
• Anti-inflammatory Studies: Applied in biochemical assays to study mechanisms of inflammation and potential therapeutic applications.
• Marine Natural Product Chemistry: Acts as a key analytical standard for the identification and quantification of saponins in marine extracts and commercial products.
• Biological Pathway Analysis: Utilized as a tool compound to probe cell signaling pathways, including those involving apoptosis and cell cycle arrest.
• Cosmeceutical Research: Investigated for potential applications in high-value skincare formulations targeting inflammation and cellular regeneration.

Basic Information

Item	Detail
Product Name	Holothurin B
CAS No.	11052-32-7
Molecular Formula	C54H85O26S2Na
Molecular Weight	1229.3 g/mol
Synonyms	Holothurin B; Holothurin B, sodium salt; Stichoposide C; Sea Cucumber Saponin B; 3β-[(O-β-D-Glucopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→4)-O-β-D-quinovopyranosyl-(1→2)-O-β-D-xylopyranosyl)oxy]-23-oxo-7,8-didehydroholost-9(11)-en-8α-yl sodium sulfate; Actinopygoside B; EINECS 234-278-9
EINECS	234-278-9

Quality Control

Our Holothurin B is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for reference standards, and our quality systems support traceability and data integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.