Description

Phenylthiohydantoin-Glutamine is a specialized derivative of glutamine, where the amino acid is conjugated with a phenylthiohydantoin moiety. This compound is of significant value in biochemical research and analytical chemistry, particularly in protein sequencing and peptide analysis workflows. It serves as a critical intermediate or reference standard for laboratories and manufacturers in the pharmaceutical, biotechnology, and life science sectors.

Application

• Protein Sequencing Reagent: Used in Edman degradation and related methods for the stepwise identification of amino acids in peptides and proteins.
• Analytical Reference Standard: Serves as a high-purity standard for calibrating analytical instruments like HPLC and mass spectrometry in proteomics research.
• Biochemical Research: Employed in studies investigating amino acid metabolism, protein structure-function relationships, and enzyme mechanisms.
• Pharmaceutical Intermediate: Acts as a key building block or precursor in the synthesis of more complex molecules for drug discovery programs.
• Peptide Synthesis & Modification: Utilized for the specific labeling or modification of glutamine residues within synthetic peptides.
• Diagnostic Kit Component: Incorporated into specialized diagnostic kits and assays for protein analysis and biomarker detection.

Basic Information

Product Name	Phenylthiohydantoin-Glutamine
CAS No.	10567-86-9
Molecular Formula	C₁₄H₁₅N₃O₃S
Molecular Weight	305.35 g/mol
Synonyms	PTH-Glutamine; Glutamine Phenylthiohydantoin; 5-(2-Amino-4-carbamoylbutanamido)-3-phenyl-2-thioxoimidazolidin-4-one; PTH-Gln; Edman Degradation Product of Glutamine; 3-Phenyl-2-thiohydantoin derivative of L-Glutamine; N-Phenylthiocarbamoyl-L-glutamine
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin-Glutamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.