Description

4-Methylene-1-Pyrazoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique reactivity profile, serving as a key precursor for constructing complex nitrogen-containing molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel drug candidates, particularly those with pyrazole or fused heterocyclic cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and dyes with specific optical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies and exploring new chemical reactions in organic chemistry.
• Custom Synthesis & Scale-up: Provides a starting point for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	4-Methylene-1-Pyrazoline
CAS No.	10496-76-1
Molecular Formula	C4H6N2
Molecular Weight	82.10 g/mol
Synonyms	1-Pyrazoline, 4-methylene-; 4-Methylenepyrazoline; 4-Methylene-δ1-pyrazoline; 4-Methylene-1,2-dihydropyrazole; 4-Methylenepyrazole (tautomer); 4-Methylenepyrazolidine (incorrect but sometimes used); 4-Methylene-2H-pyrazole
EINECS	Contact for details

Quality Control

Our 4-Methylene-1-Pyrazoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical grades: 95%, 97%, 98%)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.