Description

2,2,4-Trimethyl-3-Oxovalerylchloride is a highly reactive acid chloride derivative of trimethylpyruvic acid, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 2,2,4-trimethyl-3-oxovaleryl moiety, enabling the creation of complex molecular architectures. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key starting material or building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring branched-chain keto-acid structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that incorporate specific ketone functionalities.
• Peptide Mimetics & Modifications: Employed to acylate amino groups or modify peptide backbones to alter stability, bioavailability, or activity.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyesters, polyamides, or coatings with tailored properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and creating novel heterocyclic compounds.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic colorants and photoactive materials.

Basic Information

Product Name	2,2,4-Trimethyl-3-Oxovalerylchloride
CAS No.	10472-34-1
Molecular Formula	C8H13ClO2
Molecular Weight	176.64 g/mol
Synonyms	3,3-Dimethyl-4-oxopentanoyl Chloride; 2,2,4-Trimethyl-3-oxopentanoyl Chloride; Trimethylpyruvoyl Chloride; 4,4-Dimethyl-3-oxopentanoyl Chloride; 3-Oxo-2,2,4-trimethylpentanoyl Chloride; α,α,β-Trimethylacetoacetyl Chloride; 3,3-Dimethyl-4-oxovaleryl Chloride
EINECS	233-954-9

Quality Control

Every batch of 2,2,4-Trimethyl-3-Oxovalerylchloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from bases and oxidizing agents. Use appropriate corrosion-resistant storage equipment.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Acid Value	Contact for details
Density (at 20°C)	~1.05 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.