Description

2-Chloronicotinamide is a versatile halogenated pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the reactive chloropyridine and amide functional groups, enabling precise molecular construction for high-value compounds. This building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), including kinase inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Chemical Research & Development: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Applications: Potential intermediate for synthesizing functionalized polymers or organic electronic materials.

Basic Information

Product Name	2-Chloronicotinamide
CAS No.	10366-35-5
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	2-Chloropyridine-3-carboxamide; 3-Carbamoyl-2-chloropyridine; 2-Chloro-3-pyridinecarboxamide; 2-Chloro-3-carbamoylpyridine; 2-Chloronicotinic acid amide; Nicotinamide, 2-chloro-; 2-Chloro-nicotinamide
EINECS	Contact for details

Quality Control

Our 2-Chloronicotinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting a purity specification of ≥98% (HPLC). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.