Description

Rifazine CAS NO 10238-70-7 is a specialized chemical compound belonging to the rifamycin class of antibiotics. This product is valued for its potent biological activity, serving as a key intermediate in the synthesis of advanced pharmaceutical agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel anti-infective and anti-tuberculosis therapies. Our supply ensures high purity and consistent quality to meet the stringent demands of these critical applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of rifamycin-derived antibiotics.
• Antibiotic Research: Used in biochemical and pharmacological research to study mechanisms of action against bacterial RNA polymerase.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development and scale-up of new antibiotic formulations.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Microbiological Studies: Applied in in-vitro studies to evaluate efficacy against drug-resistant bacterial strains.

Basic Information

Product Name	Rifazine
CAS No.	10238-70-7
Molecular Formula	C43H58N4O12
Molecular Weight	822.95 g/mol
Synonyms	Rifazine; Rifamycin S piperazine; 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin SV; Rifamycin S, piperazine derivative; Rifazine (antibiotic); Antibiotic T 1384; T 1384; T-1384; L 105; L-105
EINECS	233-586-3

Quality Control

Our Rifazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	Reddish-brown to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.