Description

3-Amino-6-(Trifluoromethyl)Pyrazine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block prized for its unique trifluoromethyl and carboxylic acid functionalities. This compound is essential for medicinal chemistry research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily sought by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for creating next-generation products.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity of the pyrazine core.
• Ligand & Catalyst Development: Serves as a precursor for chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and specialty polymers.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated pyrazine derivatives.

Basic Information

Product Name	3-Amino-6-(Trifluoromethyl)Pyrazine-2-Carboxylic Acid
CAS No.	1996-45-8
Molecular Formula	C6H4F3N3O2
Molecular Weight	207.11 g/mol
Synonyms	2-Pyrazinecarboxylic acid, 3-amino-6-(trifluoromethyl)-; 3-Amino-6-(trifluoromethyl)pyrazine-2-carboxylic acid; 6-(Trifluoromethyl)-3-aminopyrazine-2-carboxylic acid; 3-Amino-6-trifluoromethylpyrazine-2-carboxylic acid; ATFPC; 3-Amino-6-trifluoromethyl-2-pyrazinecarboxylic acid
EINECS	Contact for details

Quality Control

We supply 3-Amino-6-(Trifluoromethyl)Pyrazine-2-Carboxylic Acid in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.