Description

Methyl 3-(Chlorocarbonyl)-5-Nitrobenzoate is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride and ester functional groups. This compound is essential for the synthesis of complex molecules, enabling the introduction of both nitro and ester functionalities in a single step. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring nitro-aromatic or benzoate ester motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where its reactive sites allow for further derivatization.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D labs for constructing complex organic molecules, dyes, and pigments.
• Peptide Coupling Reagent: The acid chloride group can act as a coupling agent or be used to introduce protecting groups in peptide synthesis.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.

Basic Information

Product Name	Methyl 3-(Chlorocarbonyl)-5-Nitrobenzoate
CAS No.	1955-04-0
Molecular Formula	C9H6ClNO5
Molecular Weight	243.60 g/mol
Synonyms	5-Nitroisophthalic Acid Monomethyl Ester Chloride; Methyl 5-Nitroisophthaloyl Chloride; 3-(Chlorocarbonyl)-5-nitrobenzoic Acid Methyl Ester; 5-Nitroisophthalic Acid 1-Methyl Ester 3-Acid Chloride; 1-Methyl 3-Chloroformyl-5-nitrobenzoate; 3-Carbomethoxy-5-nitrobenzoyl Chloride; Monomethyl 5-Nitroisophthaloyl Chloride; 5-Nitro-1,3-benzenedicarboxylic Acid 1-Methyl Ester 3-Acid Chloride
EINECS	217-816-8

Quality Control

Our Methyl 3-(Chlorocarbonyl)-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.