Description

Butanoyl Chloride, 3-Chloro- CAS NO 1951-11-7 is a versatile organic acid chloride derivative, serving as a critical building block in advanced chemical synthesis. Its reactive acyl chloride group enables efficient acylation and esterification reactions, making it indispensable for introducing the 3-chlorobutanoyl moiety into target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key starting material (KSM) or advanced intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a chlorinated butyryl side chain.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its structure contributes to biological activity.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with specific functional properties, such as polyamides or polyesters.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Friedel-Crafts acylation, nucleophilic substitution, and other reactions to construct complex organic molecules.
• Dye and Pigment Manufacturing: Serves as an intermediate in the synthesis of specialized dyes and colorants.
• Flavor and Fragrance Industry: Potential use in the controlled synthesis of ester compounds for aroma chemicals.

Basic Information

Product Name	Butanoyl Chloride, 3-Chloro-
CAS No.	1951-11-7
Molecular Formula	C4H6Cl2O
Molecular Weight	141.00 g/mol
Synonyms	3-Chlorobutanoyl chloride; β-Chlorobutyryl chloride; 3-Chlorobutyryl chloride; Butanoyl chloride, 3-chloro-; NSC 406079; 3-Chlorobutanoic acid chloride; 3-Chlorobutyric acid chloride; β-Chlorobutyric acid chloride
EINECS	217-795-9

Quality Control

Our Butanoyl Chloride, 3-Chloro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC or HPLC, identity confirmation (IR), and impurity profiling, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 1.0% (total)
Density (at 20°C)	~1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.