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cis-8,11,14-Eicosatrienoic Acid CAS NO 1783-84-2


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CAS No.:1783-84-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

cis-8,11,14-Eicosatrienoic Acid is a polyunsaturated fatty acid (PUFA) of significant biochemical interest, specifically an ω-6 fatty acid isomer. This compound serves as a crucial intermediate and reference standard in lipid metabolism research and the synthesis of bioactive eicosanoids. It is primarily utilized by research institutions, pharmaceutical developers, and specialty chemical manufacturers focused on metabolic studies, inflammation pathways, and the production of high-purity lipid derivatives.

Application

  • Biochemical Research Standard: Used as a high-purity reference compound in studies of fatty acid metabolism, desaturase enzyme activity, and the biosynthesis of arachidonic acid and other eicosanoids.
  • Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of lipid-based pharmaceuticals and probes targeting inflammatory and metabolic pathways.
  • Nutritional Science Studies: Employed in research to investigate the effects of specific ω-6 fatty acid isomers on cell membrane composition and signaling.
  • Analytical Chemistry: Acts as a critical calibration standard in chromatographic (GC, HPLC) and mass spectrometric analyses for lipid profiling and quantification.
  • Specialty Chemical Synthesis: Used in the synthesis of labeled compounds (e.g., deuterated or C13-labeled) for tracer studies and advanced diagnostic applications.

Basic Information

Product Name cis-8,11,14-Eicosatrienoic Acid
CAS No. 1783-84-2
Molecular Formula C₂₀H₃₄O₂
Molecular Weight 306.48 g/mol
Synonyms (8Z,11Z,14Z)-Icosa-8,11,14-trienoic Acid; Dihomo-γ-linolenic Acid (DGLA) isomer; 8Z,11Z,14Z-Eicosatrienoic Acid; all-cis-8,11,14-Eicosatrienoic Acid; 20:3, n-6 (δ8,11,14); Mead Acid isomer; 8,11,14-Eicosatrienoic Acid, (Z,Z,Z)-
EINECS 217-226-9

Quality Control

Our cis-8,11,14-Eicosatrienoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC and GC analysis, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its polyunsaturated nature, this material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures of -20°C or below for long-term stability. Avoid repeated warming to room temperature.

Specification

Item Specification
Appearance Colorless to pale yellow oil
Identification (IR / NMR) Conforms to structure
Assay (HPLC / GC) ≥ 95.0%
Related Substances Specified impurities individually ≤ 1.0%
Peroxide Value To be specified per grade
Solubility Soluble in organic solvents (e.g., ethanol, DMSO, chloroform)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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