Description

3-Bromo-1-[4-(3-Bromo-2,2-Dimethyl-Propanoyl)Piperazin-1-Yl]-2,2-Dimethyl-Propan-1-One is a high-purity, symmetrical bis-bromoalkyl piperazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring two reactive bromoalkyl groups on a piperazine core, making it an essential precursor for constructing complex molecules with specific spatial and electronic properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a precursor in the creation of new herbicides, fungicides, and plant growth regulators that require specific piperazine-based scaffolds.
• Ligand and Catalyst Development: Serves as a versatile starting material for constructing complex chelating ligands used in catalysis and material science.
• Polymer Chemistry: Can be utilized as a cross-linking agent or monomer in the synthesis of specialty polymers with tailored properties.
• Chemical Research (R&D): A valuable tool for academic and industrial research in organic methodology development and structure-activity relationship (SAR) studies.
• Bioconjugation: Potential use in linker chemistry for attaching payloads in antibody-drug conjugates (ADCs) or other bioconjugate platforms due to its reactive bromo groups.

Basic Information

Product Name	3-Bromo-1-[4-(3-Bromo-2,2-Dimethyl-Propanoyl)Piperazin-1-Yl]-2,2-Dimethyl-Propan-1-One
CAS No.	1760-15-2
Molecular Formula	C14H24Br2N2O2
Molecular Weight	412.16 g/mol
Synonyms	1,1'-(Piperazine-1,4-diyl)bis(3-bromo-2,2-dimethylpropan-1-one); 3-Bromo-2,2-dimethyl-1-(4-(3-bromo-2,2-dimethylpropanoyl)piperazin-1-yl)propan-1-one; Bis(3-bromo-2,2-dimethylpropionyl)piperazine; 1,4-Bis(3-bromo-2,2-dimethyl-1-oxopropyl)piperazine; 1760-15-2; NSC 403697; AKOS015903065
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-[4-(3-Bromo-2,2-Dimethyl-Propanoyl)Piperazin-1-Yl]-2,2-Dimethyl-Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.