Description

(2R)-2,5,7,8-Tetramethyl-2-[(3E,7E)-4,8,12-Trimethyltrideca-3,7,11-Trienyl]Chroman-6-Ol is a high-purity, synthetic form of Vitamin E, specifically the natural stereoisomer known as RRR-α-tocopherol. This compound is critical for its superior antioxidant activity and bioavailability compared to synthetic mixtures. It is an essential ingredient for manufacturers in the pharmaceutical, nutraceutical, and premium cosmetic industries seeking to enhance product stability and efficacy.

Application

• Pharmaceutical Formulations: Used as an active pharmaceutical ingredient (API) or excipient in capsules, tablets, and injectables for antioxidant therapy and nutritional supplementation.
• Dietary Supplements & Nutraceuticals: A key component in softgel capsules, multivitamin blends, and standalone antioxidant supplements.
• Premium Cosmetics & Skincare: Incorporated into anti-aging serums, creams, and lotions to protect skin from oxidative stress and improve skin barrier function.
• Functional Foods & Beverages: Used for fortification in oils, dairy alternatives, and health drinks to prevent rancidity and add nutritional value.
• Animal Nutrition (Feed Grade): Added to livestock and pet feed to support immune function, reproductive health, and meat quality.
• Research & Development: Serves as a high-purity reference standard in analytical laboratories and for biochemical research.

Basic Information

Product Name	(2R)-2,5,7,8-Tetramethyl-2-[(3E,7E)-4,8,12-Trimethyltrideca-3,7,11-Trienyl]Chroman-6-Ol
CAS No.	1721-51-3
Molecular Formula	C29H50O2
Molecular Weight	430.71 g/mol
Synonyms	D-α-Tocopherol; RRR-α-Tocopherol; Natural Vitamin E; (R,R,R)-α-Tocopherol; 2R,4'R,8'R-α-Tocopherol; 5,7,8-Trimethyltocol; Vitamin E (natural form); EINECS 217-036-0
EINECS	217-036-0

Quality Control

Our (2R)-2,5,7,8-Tetramethyl-2-[(3E,7E)-4,8,12-Trimethyltrideca-3,7,11-Trienyl]Chroman-6-Ol is manufactured under strict quality systems. We offer grades compliant with USP, Ph. Eur., and FCC monographs for pharmaceutical and food applications. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures traceability and consistency for your regulatory submissions and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at 2-8°C for long-term stability. For daily use, the product may be kept at a controlled room temperature (15-25°C) for short periods. Avoid exposure to air, heat, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, pale yellow to brownish viscous oil
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 96.0% (as RRR-α-Tocopherol)
Specific Rotation	+0.20° to +0.30° (at 20°C)
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total related substances ≤ 4.0%
Peroxide Value	≤ 5.0 meq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.