Description

Sodium 4-Phenylbutyrate is the sodium salt of 4-phenylbutyric acid, a small molecule with significant biochemical activity. This compound is valued for its role as a chemical chaperone and its ability to modulate metabolic pathways, making it a critical material in advanced research and therapeutic development. It is primarily sought after by pharmaceutical researchers, biotech companies, and manufacturers of high-purity chemical intermediates.

Application

• Pharmaceutical Intermediate: A key starting material or precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting metabolic and neurological disorders.
• Biochemical Research: Used as a chemical chaperone in cell culture and laboratory studies to reduce endoplasmic reticulum (ER) stress and protein misfolding.
• Therapeutic Development: Investigated for potential applications in treating urea cycle disorders, cystic fibrosis, and certain neurodegenerative diseases.
• Metabolic Studies: Employed as a tool compound to study fatty acid metabolism and the regulation of gene expression.
• High-Purity Chemical Synthesis: Serves as a building block for the production of more complex organic molecules in fine chemical manufacturing.

Basic Information

Product Name	Sodium 4-Phenylbutyrate
CAS No.	1716-12-7
Molecular Formula	C10H11NaO2
Molecular Weight	186.19 g/mol
Synonyms	4-Phenylbutyric Acid Sodium Salt; Sodium Phenylbutyrate; Benzenebutanoic Acid Sodium Salt; Buphenyl Sodium Salt; Ammonaps (pharmaceutical grade); PB Sodium Salt; NaPB; EINECS 217-004-9

Quality Control

Our Sodium 4-Phenylbutyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for research and development. Certificates of Analysis (COA) documenting purity, residual solvents, and heavy metals are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider desiccants or a nitrogen atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.