Description

4-tert-Butylbenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 4-tert-butylbenzoyl moiety, a key structural feature for modifying physical and chemical properties in target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients, performance materials, and liquid crystal compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring lipophilic tert-butyl aromatic groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the tert-butyl group can enhance compound activity and environmental persistence.
• Liquid Crystal Materials: Acts as a precursor for mesogenic compounds used in display technologies, leveraging the steric bulk of the tert-butyl group to influence molecular alignment and phase behavior.
• Polymer & Resin Modifier: Employed to functionalize polymers or as a monomer in polycondensation reactions to create specialty polyesters or polyamides with tailored properties.
• Organic Synthesis Reagent: A fundamental reagent for Friedel-Crafts acylation, esterification, and amidation reactions to construct complex organic architectures in research and development.
• Dye & Pigment Manufacturing: Serves as an intermediate in the synthesis of advanced colorants and photostable dyes for industrial applications.

Basic Information

Item	Detail
Product Name	4-tert-Butylbenzoyl Chloride
CAS No.	1710-98-1
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	p-tert-Butylbenzoyl Chloride; 4-(1,1-Dimethylethyl)benzoyl Chloride; 4-tert-Butylbenzoic Acid Chloride; 4-(tert-Butyl)benzoyl Chloride; 4-t-Butylbenzoyl Chloride; Benzoic acid, 4-(1,1-dimethylethyl)-, chloride; NSC 403119
EINECS	216-968-1

Quality Control

Our 4-tert-Butylbenzoyl Chloride is manufactured under stringent process controls to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, and NMR. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat and incompatible materials. Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.