Description

n-2,4-Dnp-Dl-Methionine Sulfoxide is a derivative of the amino acid methionine, specifically its sulfoxide form conjugated with 2,4-dinitrophenylhydrazine (DNP). This compound is of significant value as a key analytical standard and research chemical for studying amino acid oxidation, protein modification, and metabolic pathways. It is primarily needed by research institutions, pharmaceutical development laboratories, and analytical service providers focusing on proteomics, biomarker discovery, and the biochemical analysis of oxidative stress.

Application

• Analytical Reference Standard: Used as a high-purity standard in High-Performance Liquid Chromatography (HPLC) and mass spectrometry for the identification and quantification of methionine sulfoxide and related derivatives in complex biological matrices.
• Biochemical Research: Serves as a critical reagent in studies investigating protein oxidation, aging, and disease mechanisms where methionine sulfoxide is a known biomarker.
• Pharmaceutical Development: Employed in the research and quality control of peptide-based drugs and biopharmaceuticals to monitor and characterize oxidation-related degradation products.
• Proteomics & Metabolomics: Acts as a tool compound for method development and validation in advanced omics studies aimed at profiling post-translational modifications.
• Nutritional Science Research: Utilized in studies examining the bioavailability and metabolic fate of sulfur-containing amino acids and their oxidized forms.

Basic Information

Product Name	n-2,4-Dnp-Dl-Methionine Sulfoxide
CAS No.	1695-02-9
Molecular Formula	C11H14N4O6S
Molecular Weight	330.32 g/mol
Synonyms	2,4-Dinitrophenylhydrazone of DL-Methionine Sulfoxide; DNP-Methionine Sulfoxide; N-(2,4-Dinitrophenyl)-DL-methionine sulfoxide; Methionine Sulfoxide DNP Hydrazone; DL-Methionine Sulfoxide 2,4-Dinitrophenylhydrazone; (RS)-2-Amino-4-(methylsulfinyl)butanoic acid 2,4-dinitrophenylhydrazone
EINECS	Contact for details

Quality Control

Our n-2,4-Dnp-Dl-Methionine Sulfoxide is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the exacting standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substance profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in secondary packaging or a dark storage cabinet. For long-term storage, consider conditions under an inert atmosphere to minimize potential oxidative degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.