Description

Dnp-L-Threonine is a chemically modified derivative of the essential amino acid L-Threonine, where the 2,4-dinitrophenyl (Dnp) group is introduced. This modification is crucial for its primary role as a key intermediate and analytical reagent in advanced biochemical research and peptide synthesis. It is particularly valuable for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity building blocks for developing novel compounds or for use in chromatographic analysis and protein sequencing studies.

Application

• Peptide Synthesis Intermediate: Serves as a protected or derivatized form of threonine for the controlled synthesis of complex peptides and protein fragments.
• Biochemical Research Reagent: Used in laboratory studies involving amino acid analysis, enzyme-substrate interactions, and metabolic pathway investigations.
• Chromatographic Reference Standard: Employed as a high-purity standard in HPLC and other analytical methods for the identification and quantification of amino acids and their derivatives.
• Pharmaceutical Development: Acts as a specialized starting material or intermediate in the research and development of new therapeutic agents and diagnostic tools.
• Proteomics and Protein Sequencing: Utilized in techniques for labeling, detecting, or sequencing proteins and peptides due to the distinctive properties of the Dnp group.

Basic Information

Product Name	Dnp-L-Threonine
CAS No.	1655-65-8
Molecular Formula	C₁₀H₁₁N₃O₇
Molecular Weight	285.21 g/mol
Synonyms	N-(2,4-Dinitrophenyl)-L-threonine; (2S,3R)-2-Amino-3-hydroxy-N-(2,4-dinitrophenyl)butanamide; DNP-Thr; DNP-L-Thr; L-Threonine, N-(2,4-dinitrophenyl)-; 2,4-Dinitrophenyl-L-threonine; Dnp-Thr-OH
EINECS	Contact for details

Quality Control

Our Dnp-L-Threonine is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, chiral purity, and impurity profiles. While typically supplied as a high-grade research chemical, specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.