Description

N,S-Di(2,4-Dnp)-L-Cysteine is a specialized derivative of the amino acid L-cysteine, modified with two 2,4-dinitrophenyl (Dnp) groups. This compound is primarily valued as a key intermediate and analytical standard in biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of proteomics, enzyme inhibition studies, and the synthesis of novel bioactive molecules.

Application

• Biochemical Research: Used as a reference standard and reagent in the study of protein structure, function, and cysteine-related modifications.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of more complex drug candidates and targeted therapeutic agents.
• Proteomics & Enzyme Studies: Employed in activity-based protein profiling (ABPP) and as an inhibitor or substrate analog in enzymatic assays.
• Analytical Chemistry: Functions as a high-purity standard for method development and validation in chromatographic (HPLC, LC-MS) analyses.
• Chemical Biology Probes: Utilized in the design and development of probes for detecting and labeling thiol groups in biological systems.

Basic Information

Product Name	N,S-Di(2,4-Dnp)-L-Cysteine
CAS No.	1655-62-5
Molecular Formula	C15H12N4O8S
Molecular Weight	408.34 g/mol
Synonyms	L-Cysteine, N,S-bis(2,4-dinitrophenyl)-; N,S-Bis(2,4-dinitrophenyl)-L-cysteine; N,S-Di-DNP-L-cysteine; (2R)-2-Amino-3-[[(2,4-dinitrophenyl)sulfanyl]-(2,4-dinitrophenyl)amino]propanoic acid; 2,4-DNPH derivative of L-cysteine; N,S-Di(2,4-dinitrophenyl)-L-cysteine
EINECS	Contact for details

Quality Control

Our N,S-Di(2,4-Dnp)-L-Cysteine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, IR) for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.