Description

2-Acetoxy-2-Phenylacetyl Chloride is a highly reactive acyl chloride derivative, serving as a crucial building block in advanced organic synthesis. Its core value lies in its dual functionality, enabling efficient one-step acylation and esterification reactions to construct complex molecular architectures. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), advanced intermediates, and novel fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of β-lactam antibiotics and other pharmacologically active molecules requiring the phenylacetyl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its reactive chloride group facilitates the introduction of specific functional groups.
• Peptide Chemistry: Employed as an acylating agent for the protection of amino groups or the synthesis of modified peptide derivatives.
• Polymer Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Dye and Pigment Manufacturing: Intermediate for creating complex organic colorants and photoactive compounds.
• Academic and Industrial R&D: A versatile reagent for methodological development and the exploration of new chemical entities in research laboratories.

Basic Information

Product Name	2-Acetoxy-2-Phenylacetyl Chloride
CAS No.	1638-63-7
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	α-Acetoxy-α-phenylacetyl Chloride; (Acetoxy)(phenyl)acetyl Chloride; 2-Phenyl-2-(acetyloxy)acetyl Chloride; Mandelic Acid Acetate Chloride; O-Acetylmandelic Acid Chloride; Phenylglyoxylic Acid Acetate Chloride; α-Phenyl-α-acetoxyacetyl Chloride
EINECS	Contact for details

Quality Control

Our 2-Acetoxy-2-Phenylacetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.