Description

Methyl 3-Amino-6-Chloro-5-Hydroxypyrazine-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate in the development of complex active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of novel molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its pyrazine core for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final synthetic steps for producing specific, high-value APIs under current Good Manufacturing Practice (cGMP) conditions.
• Specialty Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals where the chlorohydroxypyrazine structure imparts specific properties.

Basic Information

Product Name	Methyl 3-Amino-6-Chloro-5-Hydroxypyrazine-2-Carboxylate
CAS No.	1503-04-4
Molecular Formula	C6H6ClN3O3
Molecular Weight	203.58 g/mol
Synonyms	Methyl 3-amino-6-chloro-5-hydroxypyrazine-2-carboxylate; 3-Amino-6-chloro-5-hydroxypyrazine-2-carboxylic acid methyl ester; Methyl 3-amino-6-chloro-5-oxo-4,5-dihydropyrazine-2-carboxylate; 6-Chloro-3-amino-5-hydroxypyrazine-2-carboxylic acid methyl ester; 2-Pyrazinecarboxylic acid, 3-amino-6-chloro-5-hydroxy-, methyl ester; Methyl 3-amino-6-chloro-5-hydroxy-2-pyrazinecarboxylate; CAS 1503-04-4
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-6-Chloro-5-Hydroxypyrazine-2-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) with full traceability are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and may be hygroscopic; therefore, containers should be kept sealed under an inert atmosphere for long-term storage to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.