Description

Glybuzole CAS NO 1492-02-0 is a synthetic organic compound belonging to the sulfonylurea class, recognized for its specific biological activity. This high-purity chemical intermediate is critical for research and development in the pharmaceutical sector, where precise molecular structure and consistent quality are paramount. It is primarily utilized by manufacturers and R&D laboratories focused on metabolic disorder research and novel therapeutic agent synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of investigational new drugs, particularly in classes targeting metabolic pathways.
• Biochemical Research: Used as a reference standard or active agent in in vitro and in vivo studies related to glucose metabolism and insulin secretion.
• Academic & Institutional R&D: Employed in university and institutional laboratories for pharmacological and mechanistic studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	Glybuzole
CAS No.	1492-02-0
Molecular Formula	C12H18N2O3S
Molecular Weight	270.35 g/mol
Synonyms	Glybuzole; N-[(Butylamino)carbonyl]-4-methylbenzenesulfonamide; 1-Butyl-3-(p-tolylsulfonyl)urea; Glybutamide; Glybuthiazol; Glibutimida; HB 419; Glybenclamide analog
EINECS	Contact for details

Quality Control

Our Glybuzole is manufactured and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.