Description

4-(Benzyloxy)Benzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the 4-(benzyloxy)benzoyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of complex intermediates, active pharmaceutical ingredients (APIs), and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the production of herbicides and fungicides, where the benzyloxybenzoyl group contributes to biological activity.
• Liquid Crystal & OLED Materials: Acts as a building block for mesogenic cores and electron-transport materials in display and lighting technologies.
• Polymer Chemistry: Employed in the synthesis of specialty polyesters, polyamides, and other high-performance polymers with specific thermal or optical properties.
• Peptide & Protein Modification: Useful as an acylating agent for modifying amino acids or introducing protecting groups in peptide synthesis.
• Dye & Pigment Manufacturing: Intermediate for creating specialized azo dyes and pigments with enhanced lightfastness and color properties.
• Cross-Coupling Reactions: Serves as an electrophile in palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Academic & Contract Research: Essential reagent for methodological development and exploratory chemistry in R&D laboratories.

Basic Information

Product Name	4-(Benzyloxy)Benzoyl Chloride
CAS No.	1486-50-6
Molecular Formula	C14H11ClO2
Molecular Weight	246.69 g/mol
Synonyms	p-(Benzyloxy)benzoyl chloride; 4-(Phenylmethoxy)benzoyl chloride; (4-Benzyloxy)benzoyl chloride; Benzyl 4-(chlorocarbonyl)phenyl ether; 4-Benzyloxybenzoic acid chloride; p-Benzyloxybenzoyl chloride; 4-(Benzyloxy)benzenecarbonyl chloride; BOB-Cl
EINECS	Contact for details

Quality Control

Our production of 4-(Benzyloxy)Benzoyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.