Description

Estra-1,3,5(10)-Triene-3,11α,17β-Triol CAS NO 1464-61-5 is a high-purity steroid derivative, specifically a trihydroxy estrogen. This compound is a critical intermediate in the synthesis of more complex steroid hormones and active pharmaceutical ingredients (APIs). It is essential for pharmaceutical R&D and manufacturing, particularly for companies developing hormone-based therapies and conducting advanced biochemical research. Its defined structure and purity make it a valuable building block for creating targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of steroidal drugs and hormone replacement therapies.
• Biochemical Research: Used as a reference standard or reagent in laboratory studies investigating estrogen metabolism, receptor binding, and endocrine pathways.
• API Development: Serves as a crucial precursor in the research and development of new Active Pharmaceutical Ingredients (APIs) within the steroid class.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for fundamental and applied research in medicinal chemistry and pharmacology.
• Reference Standard Production: Utilized by manufacturers of certified reference materials (CRMs) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	Estra-1,3,5(10)-Triene-3,11α,17β-Triol
CAS No.	1464-61-5
Molecular Formula	C18H24O3
Molecular Weight	288.38 g/mol
Synonyms	11α,17β-Dihydroxyestra-1,3,5(10)-trien-3-ol; 3,11α,17β-Trihydroxyestra-1,3,5(10)-triene; 11α-Hydroxy-17β-estradiol; 11α-Hydroxyestradiol; Estra-1,3,5(10)-triene-3,11α,17β-triol; 11α,17β-Estradiol; 3,11α,17β-Trihydroxy-1,3,5(10)-estratriene
EINECS	Contact for details

Quality Control

Our Estra-1,3,5(10)-Triene-3,11α,17β-Triol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.