Description

2-[2-[4-[(4-Chlorophenyl)Phenylmethyl]Piperazin-1-Yl]Ethoxy]Ethanol Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the synthesis of advanced active pharmaceutical ingredients (APIs) and for biochemical research applications. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and antihistamine research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route for specific, high-value APIs.
• Biochemical Research: Serves as a standard or reagent in pharmacological and metabolic pathway studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Used in analytical laboratories for method development and quality control testing.
• Academic Research: Employed in university and institutional labs for medicinal chemistry and drug discovery programs.

Basic Information

Product Name	2-[2-[4-[(4-Chlorophenyl)Phenylmethyl]Piperazin-1-Yl]Ethoxy]Ethanol Hydrochloride
CAS No.	1244-76-4
Molecular Formula	C21H27ClN2O2•HCl
Molecular Weight	411.37 g/mol
Synonyms	Hydroxyzine Impurity C; 2-[2-[4-[(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl]ethoxy]ethanol hydrochloride; Cetirizine Related Compound C; 1-(2-{2-[4-(4-Chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy}ethyl) Alcohol Hydrochloride; Hydroxyzine EP Impurity C; Hydroxyzine Related Compound C; Cetirizine Impurity C; Hydroxyzine Hydrochloride Impurity C
EINECS	Contact for details

Quality Control

Our 2-[2-[4-[(4-Chlorophenyl)Phenylmethyl]Piperazin-1-Yl]Ethoxy]Ethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and relevant pharmacopeial standards (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.