Description

4-Chloro-3-Fluoro-2-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of functional organic materials, including liquid crystals and electronic chemicals.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-3-Fluoro-2-Methylpyridine
CAS No.	1195-25-1
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Methyl-4-chloro-3-fluoropyridine; 3-Fluoro-4-chloro-2-methylpyridine; 4-Chloro-3-fluoro-2-picoline; 2-Picoline, 4-chloro-3-fluoro-; 1195-25-1; 4-Chloro-3-fluoro-2-methylpyridine; 3-Fluoro-4-chloro-2-methylpyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluoro-2-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, such as cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.