Description

1-Pyrrolidinecarbonyl Chloride is a versatile and highly reactive acid chloride derivative of pyrrolidine, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the pyrrolidinecarbonyl moiety, a key structural feature in numerous bioactive molecules. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create novel amides and functionalized intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrrolidine-based amide functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that incorporate heterocyclic amide structures for enhanced efficacy.
• Peptide Mimetics & Drug Discovery: Employed to create peptidomimetic compounds and novel chemical entities during medicinal chemistry research and lead optimization.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers with specific functional groups.
• Material Science: Utilized in surface modification and the creation of advanced organic materials with tailored properties.
• Chemical Research: Serves as a fundamental reagent in academic and industrial laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	1-Pyrrolidinecarbonyl Chloride
CAS No.	1192-63-8
Molecular Formula	C5H8ClNO
Molecular Weight	133.57 g/mol
Synonyms	Pyrrolidine-1-carbonyl chloride; 1-Carbamoylpyrrolidine chloride; Pyrrolidine-1-carboxylic acid chloride; N-Carboxypyrrolidine chloride; Pyrrolidinecarboxylic acid chloride; 1-Pyrrolidinecarboxylic acid chloride; N-(Chlorocarbonyl)pyrrolidine
EINECS	214-754-5

Quality Control

Our 1-Pyrrolidinecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use in fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.