Description

Buformin Hydrochloride is a high-purity pharmaceutical active ingredient belonging to the biguanide class of compounds. It is a critical intermediate and reference standard for research and development in metabolic and endocrine disorders. This compound is essential for pharmaceutical manufacturers, research institutions, and analytical laboratories focused on diabetes research and drug development. Our supply ensures consistent quality and reliable availability for global B2B partners.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active pharmaceutical substance in the formulation of antidiabetic medications.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical testing laboratories.
• Biochemical Research: Used in metabolic studies to investigate mechanisms of action related to glucose metabolism and insulin sensitivity.
• Preclinical & Clinical Research: Employed as a key material in the development and testing of new therapeutic agents for type 2 diabetes.
• Chemical Synthesis Intermediate: Acts as a crucial building block for the synthesis of novel biguanide derivatives and related compounds.

Basic Information

Product Name	Buformin Hydrochloride
CAS No.	1190-53-0
Molecular Formula	C6H15N5•HCl
Molecular Weight	209.68 g/mol
Synonyms	Buformin HCl; 1-Butylbiguanide Hydrochloride; N-Butylbiguanide Hydrochloride; Silubin; Glybigidum; DB 1; DB-1; Buformini Hydrochloridum
EINECS	214-730-6

Quality Control

Our Buformin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for API manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.