Description

1-Benzothiophene-5-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound matters as a key building block for introducing the benzothiophene moiety into more complex molecular architectures, enabling the development of novel materials and active compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new drug candidates, crop protection agents, and functional organic materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the benzothiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic semiconductors, conductive polymers, and advanced organic frameworks.
• Ligand and Catalyst Development: Employed to synthesize complex chelating ligands for catalysis and metal-organic chemistry applications.
• Fluorescent Dye and Sensor Precursor: Acts as a starting material for developing benzothiophene-based fluorophores and molecular sensors.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses serving diverse R&D needs.

Basic Information

Product Name	1-Benzothiophene-5-Carbonyl Chloride
CAS No.	1128-89-8
Molecular Formula	C9H5ClOS
Molecular Weight	196.65 g/mol
Synonyms	5-Benzothienoyl chloride; 1-Benzothiophene-5-carboxylic acid chloride; Benzo[b]thiophene-5-carbonyl chloride; 5-Carboxybenzothiophene chloride; Thianaphthene-5-carbonyl chloride; 5-Benzothiophenecarbonyl chloride; 5-(Chlorocarbonyl)benzo[b]thiophene
EINECS	Contact for details

Quality Control

Our 1-Benzothiophene-5-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, alcohols, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.