Description

1,3-Dimethyl-8-(Pyridin-4-Yl)-1H-Purine-2,6(3H,7H)-Dione is a high-purity, heterocyclic organic compound belonging to the xanthine derivative family, distinguished by its pyridine-substituted purine-dione core structure. This compound serves as a critical advanced intermediate or reference standard in pharmaceutical research and development, enabling the synthesis of novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in developing new drug candidates, particularly in areas targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel adenosine receptor antagonists and other purine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or ligand in enzymatic studies and receptor binding assays to investigate purinergic signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity for new drug candidates.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for high-value agrochemicals or specialty materials.
• Academic Research: Utilized in universities and R&D labs for fundamental studies on heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	1,3-Dimethyl-8-(Pyridin-4-Yl)-1H-Purine-2,6(3H,7H)-Dione
CAS No.	1088-64-8
Molecular Formula	C12H11N5O2
Molecular Weight	257.25 g/mol
Synonyms	8-(4-Pyridyl)-1,3-dimethylxanthine; 1,3-Dimethyl-8-(4-pyridinyl)-3,7-dihydro-1H-purine-2,6-dione; 8-(Pyridin-4-yl)-1,3-dimethylxanthine; 1,3-Dimethyl-8-(4-pyridyl)xanthine; 4-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-8-yl)pyridine; 8-(4-Pyridinyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione; 1,3-Dimethyl-8-(4-pyridinyl)-1H-purine-2,6(3H,7H)-dione
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-8-(Pyridin-4-Yl)-1H-Purine-2,6(3H,7H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with research and pharmaceutical grade standards. Comprehensive Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.