Description

Sodium Acetylide is a highly reactive organometallic compound, primarily used as a potent nucleophilic acetylene transfer agent in organic synthesis. Its core value proposition lies in enabling efficient carbon-carbon bond formation, particularly for the synthesis of terminal and internal alkynes, which are crucial building blocks in pharmaceuticals and advanced materials. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce acetylene units into complex molecular frameworks. Sodium Acetylide CAS NO 1066-26-8 is typically supplied as a suspension or solid, requiring careful handling due to its reactive nature.

Application

• Pharmaceutical Intermediates: Key reagent for synthesizing alkyne-containing active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate acetylene motifs.
• Material Science: Building block for conjugated polymers, molecular wires, and organic electronic materials requiring precise alkyne linkages.
• Fine Chemical Production: Employed in the manufacture of vitamins, fragrances, and dyes where acetylene groups are integral.
• Organic Synthesis: Fundamental reagent for nucleophilic addition reactions, alkylations, and the synthesis of substituted acetylenes.
• Research & Development: Critical tool in academic and industrial labs for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	Sodium Acetylide
CAS No.	1066-26-8
Molecular Formula	C2HNa
Molecular Weight	48.03 g/mol
Synonyms	Monosodium acetylide; Ethynylsodium; Sodium ethynide; Sodium acetylide suspension; Acetylene sodium derivative; Carbide, sodium (C2HNa); Sodium acetylide in mineral oil
EINECS	213-922-6

Quality Control

Our Sodium Acetylide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. While specific purity grades (e.g., reagent grade, suspension concentration in toluene or mineral oil) are available, all material is characterized to confirm identity and reactivity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, solvent content, and reactivity tests. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and hygroscopic nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for extended stability. Isolate from moisture, air, strong oxidizers, and acids. Containers must be kept sealed and handled with appropriate precautions to prevent exposure to atmospheric conditions.

Specification

Item	Specification
Appearance	Grayish suspension or solid
Identification (IR)	Conforms
Assay (as C2HNa)	Contact for details
Solvent Content (if applicable)	Contact for details
Reactivity Test	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.