Description

Nalorphine Hydrobromide is a specialized pharmaceutical salt of the opioid antagonist nalorphine. This compound is of significant importance in pharmacological research and development, particularly in the study of opioid receptor interactions and the development of treatments for substance abuse. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical and life sciences industries. Its precise chemical identity is confirmed by CAS NO 1041-90-3.

Application

• Primary use as a pharmacological reference standard for analytical and research purposes.
• Key intermediate in the synthesis and development of novel opioid antagonists and related therapeutic agents.
• Essential material for in-vitro and in-vivo research studying opioid receptor mechanisms and signal transduction.
• Used in the preparation of calibration standards for analytical methods like HPLC and LC-MS in quality control laboratories.
• Critical component in preclinical studies investigating treatments for opioid overdose and dependency.
• Supplies the fine chemical and pharmaceutical manufacturing sectors with a high-purity building block.

Basic Information

Product Name	Nalorphine Hydrobromide
CAS No.	1041-90-3
Molecular Formula	C₁₉H₂₂BrNO₃
Molecular Weight	392.29 g/mol
Synonyms	N-Allylnormorphine Hydrobromide; N-Allylnorcodeinone Hydrobromide; N-Allyl-N-desmethylmorphine Hydrobromide; 17-Allyl-7,8-didehydro-4,5α-epoxymorphinan-3,6α-diol Hydrobromide; Nalorphine HBr; Lethidrone Hydrobromide; NANM Hydrobromide
EINECS	213-875-8

Quality Control

Our Nalorphine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We support compliance with global regulatory frameworks for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.