Description

3H-Azirine is a highly reactive, strained three-membered heterocyclic compound containing a carbon-nitrogen double bond, serving as a versatile and valuable synthetic building block in advanced organic chemistry. Its unique structure makes it a crucial precursor for constructing complex nitrogen-containing molecules, enabling the synthesis of novel pharmaceuticals, agrochemicals, and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and specialty chemical industries seeking to develop new active ingredients and sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of complex nitrogen heterocycles found in active pharmaceutical ingredients (APIs), including potential antibiotics and neurological agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific nitrogen-based ring systems.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating polymers with unique properties, such as specialized coatings or adhesives.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological processes.
• Academic & Industrial R&D: Serves as a fundamental reagent in methodological development and discovery chemistry for exploring new reaction pathways.
• Ligand & Catalyst Precursor: Utilized in the synthesis of novel ligands and organocatalysts for asymmetric synthesis and metal complexation.

Basic Information

Item	Detail
Product Name	3H-Azirine
CAS No.	157-16-4
Molecular Formula	C2H3N
Molecular Weight	41.05 g/mol
Synonyms	Azacyclopropene; 1H-Azirine; 2H-Azirine; Azirine; Vinylenimine; Ethylenimine, 1-aza-; 1-Aza-2,3-dihydrocyclopropene; 1-Azacycloprop-2-ene
EINECS	205-858-5

Quality Control

Every batch of 3H-Azirine is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support customers requiring material for cGMP intermediates or advanced non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C). Keep the container in a cool, dry, well-ventilated place, away from heat and ignition sources. Handle and open containers with care to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.