Description

2-Bromopyridine is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. Its primary value lies in its reactivity as an electrophile, enabling the formation of new carbon-carbon and carbon-nitrogen bonds through cross-coupling reactions. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis (e.g., Suzuki, Negishi couplings).
• Material Science Research: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A fundamental reagent for method development in cross-coupling chemistry and heterocyclic compound synthesis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex dyes, flavors, and fragrances.

Basic Information

Product Name	2-Bromopyridine
CAS No.	109-04-6
Molecular Formula	C5H4BrN
Molecular Weight	157.99 g/mol
Synonyms	2-Bromopyridine; α-Bromopyridine; Pyridine, 2-bromo-; o-Bromopyridine; 2-Pyridyl bromide; NSC 8758; Bromopyridine (2-); 2-BrPy
EINECS	203-642-9

Quality Control

Our 2-Bromopyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.5680 - 1.5720
Density (20°C)	1.650 - 1.670 g/mL
Boiling Point	193 - 195 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.