Description

Phenylacetyl Chloride is a versatile and highly reactive organic acid chloride, essential for introducing the phenylacetyl functional group into target molecules. Its primary value lies in its role as a key acylating and building block agent in sophisticated organic syntheses. This compound is critically needed by manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the production of active ingredients, fragrances, and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of β-lactam antibiotics, including semisynthetic penicillins and cephalosporins.
• Agrochemical Synthesis: Used in the production of certain herbicides, fungicides, and plant growth regulators.
• Fragrance and Flavor Industry: Serves as a precursor for phenylacetic acid esters, which are important aroma compounds.
• Peptide Chemistry: Employed as an acylating agent for the protection of amino groups or the synthesis of modified peptides.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers and resins.
• Organic Synthesis Reagent: A fundamental reagent for Friedel-Crafts acylation and other reactions to form ketones and amides.

Basic Information

Product Name	Phenylacetyl Chloride
CAS No.	103-80-0
Molecular Formula	C8H7ClO
Molecular Weight	154.59 g/mol
Synonyms	2-Phenylacetyl Chloride; Phenacetyl Chloride; α-Toluoyl Chloride; Benzeneacetyl Chloride; (Phenylacetyl) Chloride; ω-Chloroacetophenone; PAC; Phenylacetic Acid Chloride
EINECS	203-148-6

Quality Control

Our Phenylacetyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality documentation, including detailed Certificates of Analysis (COA) for each lot, verifying parameters such as assay, identity, and impurity profiles. Our production adheres to cGMP principles where applicable, ensuring suitability for demanding applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat, ignition sources, and incompatible materials such as strong bases, alcohols, and oxidizing agents. Due to its hygroscopic and highly volatile nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to maintain product integrity. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Free Acid (as Phenylacetic Acid)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.