Description

Lixisenatide CAS NO 827033-10-3 is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist, representing a significant advancement in peptide-based therapeutics. This compound is crucial for its role in regulating blood glucose levels by enhancing glucose-dependent insulin secretion. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for type 2 diabetes.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of injectable anti-diabetic medications.
• Pharmaceutical Research & Development for studying GLP-1 receptor mechanisms and metabolic pathways.
• Reference Standard for quality control and analytical method development in regulatory and laboratory settings.
• Preclinical and Clinical Studies to evaluate efficacy, pharmacokinetics, and safety profiles.
• Bulk Drug Substance for contract manufacturing organizations (CMOs) producing finished dosage forms.
• Biochemical Research as a tool compound for endocrinology and peptide hormone studies.

Basic Information

Product Name	Lixisenatide
CAS No.	827033-10-3
Molecular Formula	C₂₁₅H₃₄₇N₆₁O₆₅S
Molecular Weight	4858.4 g/mol
Synonyms	LY2189265; AVE0010; ZP10A; GLP-1 (7-37) amide, Lys26-(Nε-(γ-Glu-(Nα-hexadecanoyl)))-Arg34; Lixisenatide acetate; Glucagon-like peptide 1 (7-37) amide, 26-L-lysine(6-(N6-(N-(1-oxohexadecyl)-L-γ-glutamyl)))-34-L-arginine-
EINECS	Contact for details

Quality Control

Our Lixisenatide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, mass spectrometry for identity confirmation, and tests for residual solvents and endotoxins. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP and ICH guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled temperature of 2°C to 8°C (refrigerated). Due to its hygroscopic nature, the product must be stored in a dry environment. For long-term storage, consider desiccated conditions or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetic Acid Content (HPLC)	5.0% - 12.0%
Peptide Content (UV)	≥ 80.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.