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O-3,4,6-Tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-2)-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-4)]-O-3,6-di-O-(phenylmethyl)-α-D-mannopyranosyl-(1-3)-O-[O-3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-2)-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-6)]-3,4-di-O-acetyl-α-D-mannopyranosyl-(1-6)]-O-2,4-di-O-acetyl-β-D-mannopyranosyl-(1-4)-O-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylmethyl)-β-D-glucopyranosyl-(1-4)-O-[6-deoxy-2,3,4-tris-O-(phenylmethyl)-α-L-galactopyranosyl-(1-6)]-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-β-D-glucopyranose CAS NO 946164-28-9
Unit Price:
CAS No.:946164-28-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
O-3,4,6-Tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-2)-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-4)]-O-3,6-di-O-(phenylmethyl)-α-D-mannopyranosyl-(1-3)-O-[O-3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-2)-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-6)]-3,4-di-O-acetyl-α-D-mannopyranosyl-(1-6)]-O-2,4-di-O-acetyl-β-D-mannopyranosyl-(1-4)-O-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylmethyl)-β-D-glucopyranosyl-(1-4)-O-[6-deoxy-2,3,4-tris-O-(phenylmethyl)-α-L-galactopyranosyl-(1-6)]-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-β-D-glucopyranose is a highly complex, synthetic oligosaccharide derivative, primarily utilized as a critical intermediate in advanced pharmaceutical research and development. Its intricate structure, featuring multiple protected sugar moieties and phthalimido groups, makes it an essential building block for the synthesis of complex glycoconjugates and carbohydrate-based therapeutics. This compound is of significant interest to research institutions and pharmaceutical companies engaged in the development of novel vaccines, targeted drug delivery systems, and diagnostic agents.
Application
- Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and glycoconjugate vaccines.
- Glycobiology Research: Used as a sophisticated tool compound for studying carbohydrate-protein interactions, enzyme mechanisms, and cell signaling pathways.
- Vaccine Development: Serves as a crucial building block for constructing antigenic oligosaccharide structures used in conjugate vaccine candidates against bacterial pathogens.
- Drug Delivery Systems: Employed in the design and synthesis of targeted drug carriers, where the carbohydrate moiety facilitates specific cell recognition.
- Diagnostic Reagent Synthesis: Used to create labeled carbohydrate probes for use in immunoassays, flow cytometry, and imaging studies.
- Chemical Biology Probes: Acts as a substrate or inhibitor for glycosyltransferases and glycosidases in mechanistic and high-throughput screening studies.
Basic Information
| Item | Details |
|---|---|
| Product Name | O-3,4,6-Tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-2)-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-4)]-O-3,6-di-O-(phenylmethyl)-α-D-mannopyranosyl-(1-3)-O-[O-3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-2)-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl-(1-6)]-3,4-di-O-acetyl-α-D-mannopyranosyl-(1-6)]-O-2,4-di-O-acetyl-β-D-mannopyranosyl-(1-4)-O-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3,6-bis-O-(phenylmethyl)-β-D-glucopyranosyl-(1-4)-O-[6-deoxy-2,3,4-tris-O-(phenylmethyl)-α-L-galactopyranosyl-(1-6)]-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-β-D-glucopyranose |
| CAS No. | 946164-28-9 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | Complex Oligosaccharide Phthalimide Intermediate; Protected Heptasaccharide Phthalimide Derivative; Glycosyl Donor/Acceptor Building Block; Phthalimido-protected Oligosaccharide; CAS 946164-28-9; Benzylated/Acetylated Sugar Intermediate; Carbohydrate-based Pharmaceutical Intermediate; Synthetic Glycoconjugate Precursor |
| EINECS | Contact for details |
Quality Control
This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and structural integrity, critical for downstream pharmaceutical applications. Each lot is characterized using advanced analytical techniques including NMR (1H, 13C), High-Resolution Mass Spectrometry (HRMS), and HPLC to confirm identity and purity. Comprehensive Certificates of Analysis (COA) detailing all analytical results are provided with every shipment. Our quality system is designed to support GMP-for-intermediate standards where required for regulatory filings.
Storage
Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below to ensure long-term stability of this complex, hygroscopic compound. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress. The storage area should be dry and well-ventilated.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Area %) |
| Water Content (KF) | ≤ 1.0 % |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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