Description

1-Bromo-2-Chloro-3-Methylbenzene is a halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its precise substitution pattern, which allows for regioselective functionalization and the construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for constructing complex heterocycles and substituted benzene cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen and methyl groups act as handles for further modification.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and specialty polymers due to its aromatic and halogenated structure.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi couplings) for carbon-carbon bond formation, leveraging the bromine substituent.
• Ligand and Catalyst Preparation: Utilized to synthesize specialized phosphine or nitrogen-based ligands for asymmetric catalysis and metal complexation.
• Dye and Pigment Intermediate: Functions as a starting material for the creation of complex chromophores and high-performance pigments.

Basic Information

Product Name	1-Bromo-2-Chloro-3-Methylbenzene
CAS No.	97329-43-6
Molecular Formula	C7H6BrCl
Molecular Weight	205.48 g/mol
Synonyms	2-Chloro-3-methylbromobenzene; 2-Chloro-1-bromo-3-methylbenzene; 3-Methyl-1-bromo-2-chlorobenzene; 1-Bromo-2-chloro-m-xylene; 2-Bromo-1-chloro-3-methylbenzene; Bromochloromethylbenzene; (2-Chloro-3-methylphenyl)bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-3-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.