Description

1H-Indole-1-carboxylic acid, 2-borono-5-[2-[[(1,1-dimethylethyl)dimethylyl]oxy]-3-[[2-[[(1,1-dimethylethyl)dimethylyl]oxy]ethyl]ethylamino]propoxy]-, 1-(1,1-dimethylethyl) ester is a sophisticated, multi-functional organic compound featuring indole, boronic acid, and silyl-protected hydroxyl groups. This molecule is of significant value as a key synthetic intermediate or building block in advanced organic synthesis, particularly for pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex heterocyclic frameworks.
• Proteolysis-Targeting Chimera (PROTAC) Development: The boronic acid moiety can be utilized in the construction of linker elements or warheads for targeted protein degradation platforms.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a specialized boronic ester reagent for palladium-catalyzed cross-coupling to form carbon-carbon bonds, essential for constructing complex molecules.
• Chemical Biology Probe Synthesis: Used in the development of molecular probes for studying biological pathways and protein functions due to its modifiable functional groups.
• Agrochemical Research: Employed as an intermediate in the discovery and synthesis of new active ingredients for crop protection.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or advanced polymers with specific functional properties.

Basic Information

Product Name	1H-Indole-1-carboxylic acid, 2-borono-5-[2-[[(1,1-dimethylethyl)dimethylyl]oxy]-3-[[2-[[(1,1-dimethylethyl)dimethylyl]oxy]ethyl]ethylamino]propoxy]-, 1-(1,1-dimethylethyl) ester
CAS No.	913388-77-9
Molecular Formula	C31H55BN2O6Si2
Molecular Weight	619.76 g/mol
Synonyms	tert-Butyl 2-borono-5-[2-[(tert-butyldimethylsilyl)oxy]-3-[[2-[(tert-butyldimethylsilyl)oxy]ethyl]ethylamino]propoxy]-1H-indole-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-borono-5-[2-[(tert-butyldimethylsilyl)oxy]-3-[[2-[(tert-butyldimethylsilyl)oxy]ethyl]ethylamino]propoxy]indole; BOC-Indole-Boronic Acid TBDMS Ester Derivative; 913388-77-9; 1H-Indole-1-carboxylic acid, 2-borono-5-[2-[[(1,1-dimethylethyl)dimethylyl]oxy]-3-[[2-[[(1,1-dimethylethyl)dimethylyl]oxy]ethyl]ethylamino]propoxy]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for each lot are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.