Description

(Z)-Ethyl-2-Ethoxy-3-((2'-(N'-Hydroxycarbamimidoyl) Biphenyl-4-Yl) Methyl)-3H-Benzo[D] Imidazole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound matters because it provides a reliable and consistent building block for the development of novel active pharmaceutical ingredients (APIs), ensuring research and production timelines are met. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules, particularly those targeting specific receptor activity.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Chemical Biology Probe Development: Used in the design and synthesis of molecular probes for studying enzyme inhibition and cellular signaling pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the scale-up and cGMP production of clinical trial materials.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	(Z)-Ethyl-2-Ethoxy-3-((2'-(N'-Hydroxycarbamimidoyl) Biphenyl-4-Yl) Methyl)-3H-Benzo[D] Imidazole-4-Carboxylate
CAS No.	1397836-41-7
Molecular Formula	C28H28N4O4
Molecular Weight	484.55 g/mol
Synonyms	Ethyl (Z)-2-ethoxy-3-{[2'-(N-hydroxycarbamimidoyl)biphenyl-4-yl]methyl}-3H-benzimidazole-4-carboxylate; Benzimidazole-4-carboxylic acid, 3-[[2'-(amino(hydroxyimino)methyl)[1,1'-biphenyl]-4-yl]methyl]-2-ethoxy-, ethyl ester, (3Z)-; UNII-5J8K1Q0G8I; 5J8K1Q0G8I; (Z)-Ethyl 2-ethoxy-3-((2'-(N-hydroxycarbamimidoyl)biphenyl-4-yl)methyl)-3H-benzo[d]imidazole-4-carboxylate; (Z)-Ethyl 2-ethoxy-3-{[2'-(N-hydroxycarbamimidoyl)biphenyl-4-yl]methyl}-3H-1,3-benzodiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. Our quality management system supports the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.