Description

5,8-Bis[[[5-[[bis(carboxymethyl)amino]methyl]-3-carboxy-1,2,3,4-tetrahydro-6,7-dihydroxyisoquinolin]-8-yl]methyl]-1,2,3,4-tetrahydro-6,7-dihydroxy-3-isoquinolinecarboxylic acid is a high-purity, complex organic compound of significant interest in advanced chemical research and development. This molecule is valued for its unique polyfunctional structure, featuring multiple carboxylic acid and catechol groups, which makes it a versatile chelating agent and building block. It is primarily sought after by researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for developing novel metal-binding therapeutics, diagnostic agents, and high-performance materials.

Application

• Pharmaceutical Research: As a potential active pharmaceutical ingredient (API) intermediate or a chelating agent in the development of novel metal-based therapeutics and diagnostic imaging contrast agents.
• Biotechnology: Utilized in the synthesis of specialized probes, sensors, or affinity tags that require strong and specific metal ion coordination.
• Chemical Synthesis: Serves as a sophisticated multidentate ligand or building block for creating complex macromolecules, polymers, or metal-organic frameworks (MOFs) with tailored properties.
• Analytical Chemistry: Employed in the preparation of chelating resins or reagents for the selective extraction, separation, or detection of specific metal ions from complex matrices.
• Material Science: Investigated for use in creating advanced functional materials where precise control over metal ion integration is critical for catalytic, magnetic, or optical performance.

Basic Information

Item	Details
Product Name	5,8-Bis[[[5-[[bis(carboxymethyl)amino]methyl]-3-carboxy-1,2,3,4-tetrahydro-6,7-dihydroxyisoquinolin]-8-yl]methyl]-1,2,3,4-tetrahydro-6,7-dihydroxy-3-isoquinolinecarboxylic acid
CAS No.	83708-17-2
Molecular Formula	C48H52N6O22
Molecular Weight	1088.96 g/mol
Synonyms	1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, DO3A-tris(tert-butyl ester) derivative (related precursor); Hexadentate Catecholamide Chelator; Polyamino Polycarboxylic Acid Derivative; Tetrahydroisoquinoline-based Chelating Agent; H6L (generic ligand notation); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of this high-value compound is produced and analyzed under strict quality protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical research and development projects. Our quality systems are designed to support cGMP and ISO standards where required, guaranteeing the reliability and specification adherence you need for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.