Description

3,4-Dihydroxyphenylacetic Acid is a significant catechol derivative and metabolite of dopamine, widely utilized in biochemical research and pharmaceutical development. Its role as a key intermediate and analytical standard makes it essential for studying neurological pathways and oxidative processes. This high-purity compound is critical for researchers and manufacturers in the pharmaceutical, life sciences, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Biochemical Research: Used extensively as a reference standard and reagent in the study of dopamine metabolism, oxidative stress, and neurodegenerative diseases.
• Analytical Chemistry: Serves as a crucial standard in High-Performance Liquid Chromatography (HPLC) and other analytical methods for quantifying catecholamines and related metabolites.
• Antioxidant Studies: Employed in research models to investigate antioxidant mechanisms and free radical scavenging activity due to its catechol structure.
• Enzymology: Acts as a substrate for enzymes like polyphenol oxidases and catechol-O-methyltransferase (COMT) in enzymatic assays and kinetic studies.
• Fine Chemical Synthesis: A versatile starting material for synthesizing more complex organic compounds, including specialty polymers and ligands.

Basic Information

Product Name	3,4-Dihydroxyphenylacetic Acid
CAS No.	102-32-9
Molecular Formula	C8H8O4
Molecular Weight	168.15 g/mol
Synonyms	3,4-DHPA; DOPAC; 2-(3,4-Dihydroxyphenyl)acetic Acid; Homoprotocatechuic Acid; 3,4-Dihydroxybenzeneacetic Acid; 4-Hydroxy-3-methoxyphenylacetic Acid (related metabolite); 2-(3,4-Dihydroxyphenyl)ethanoic Acid
EINECS	203-027-7

Quality Control

Our 3,4-Dihydroxyphenylacetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged exposure to air should be minimized. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	128°C - 132°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.