Description

(1S,βR)-4-Carboxy-5-[[(1S,4S)-3,3-dimethyl-2-oxo-7-oxabicyclo[2.2.1]heptan-1-yl]methyl]-2,6,7,7a-tetrahydro-7β-hydroxy-β,1,7aα-trimethyl-1H-indene-1α-propanoic acid is a high-purity, complex organic compound featuring a unique bicyclic lactone structure fused with an indene-propanoic acid moiety. This compound is of significant interest as a key chiral intermediate or building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, stereochemically defined target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, especially in therapeutic areas requiring complex molecular architectures.
• Advanced Organic Synthesis: Used in research and development for constructing complex natural product analogs and other stereochemically challenging molecules.
• Chemical Biology Research: Serves as a probe or precursor in the study of biological pathways and enzyme interactions due to its specific stereochemistry and functional groups.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) requiring this specific molecular framework.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in related chemical processes.

Basic Information

Item	Details
Product Name	(1S,βR)-4-Carboxy-5-[[(1S,4S)-3,3-dimethyl-2-oxo-7-oxabicyclo[2.2.1]heptan-1-yl]methyl]-2,6,7,7a-tetrahydro-7β-hydroxy-β,1,7aα-trimethyl-1H-indene-1α-propanoic acid
CAS No.	83216-10-8
Molecular Formula	C27H36O7
Molecular Weight	472.57 g/mol
Synonyms	4-Carboxy-5-[[(1S,4S)-3,3-dimethyl-2-oxo-7-oxabicyclo[2.2.1]heptan-1-yl]methyl]-2,6,7,7a-tetrahydro-7β-hydroxy-β,1,7aα-trimethyl-1H-indene-1α-propanoic acid, (1S,βR)-; 83216-10-8; Bicyclo[2.2.1]heptane-1-propanoic acid derivative; 7-Oxabicyclo[2.2.1]heptane-1-acetic acid, indene derivative; Lactone-indene-propanoic acid conjugate; (1S,4S)-Camphanic acid indene derivative; Chiral indene-propanoic acid intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, enantiomeric excess, and impurity profile to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.