Description

(S)-(+)-Isoproterenol L(+)-Bitartrate is the high-purity enantiomer of the classic β-adrenergic receptor agonist, isoproterenol. This specific stereoisomer is critical for research and development where precise receptor interaction and pharmacological activity are required. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and manufacturers of reference standards and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the quality control and assay of isoproterenol-based drug products and intermediates.
• Biochemical Research: Used as a selective β1- and β2-adrenergic receptor agonist in cardiovascular, pulmonary, and metabolic studies to investigate receptor signaling pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: A key chiral building block in the synthesis of enantiomerically pure cardiovascular and bronchodilator medications.
• Analytical Method Development: Employed for calibrating HPLC, LC-MS, and other chromatographic systems in pharmacokinetic and bioanalytical studies.
• Cell Culture & In Vitro Studies: Applied in physiological experiments to stimulate adenylate cyclase activity and increase intracellular cyclic AMP levels.

Basic Information

Product Name	(S)-(+)-Isoproterenol L(+)-Bitartrate
CAS No.	14638-70-1
Molecular Formula	C11H17NO3 • C4H6O6
Molecular Weight	403.38 g/mol
Synonyms	(S)-Isoproterenol Bitartrate; L-Isoproterenol Bitartrate; (-)-Isoprenaline Bitartrate; (S)-(-)-1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol Bitartrate; Isoprenaline Acid Tartrate; Isoproterenol L-Tartrate; (S)-(+)-1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanol (2R,3R)-2,3-dihydroxybutanedioate (1:1)
EINECS	Contact for details

Quality Control

Our (S)-(+)-Isoproterenol L(+)-Bitartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.