Description

8,8a-Bis(acetyloxy)-2a-[(acetyloxy)methyl]-1,1a,1b,1c,2a,3,3a,6a,6b,7,8,8a-dodecahydro-3,3a,6b-trihydroxy-1,1,5,7-tetramethyl-4H-cyclopropa[5',6']benz[1',2':7,8]azuleno[5,6-b]oxiren-4-one is a complex, high-purity diterpenoid derivative with significant biological activity. This compound is valued for its role as a key synthetic intermediate in the development of novel pharmaceutical agents, particularly in oncology and anti-inflammatory research. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in advanced organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel diterpenoid-based therapeutic agents.
• Oncology Research: Used in the development and study of potential anti-cancer compounds targeting specific cellular pathways.
• Anti-inflammatory Drug Discovery: Serves as a building block for molecules being evaluated for their immunomodulatory properties.
• Chemical Biology: Employed as a probe or tool compound to study enzyme interactions and biological mechanisms.
• Process Chemistry & Scale-up: Used in optimizing synthetic routes for the commercial production of complex active pharmaceutical ingredients (APIs).
• Academic Research: A valuable compound for universities and research institutes studying natural product synthesis and medicinal chemistry.

Basic Information

Product Name	8,8a-Bis(acetyloxy)-2a-[(acetyloxy)methyl]-1,1a,1b,1c,2a,3,3a,6a,6b,7,8,8a-dodecahydro-3,3a,6b-trihydroxy-1,1,5,7-tetramethyl-4H-cyclopropa[5',6']benz[1',2':7,8]azuleno[5,6-b]oxiren-4-one
CAS No.	77646-26-5
Molecular Formula	C30H38O11
Molecular Weight	574.62 g/mol
Synonyms	Taxinine M; 2α,5,10β,14β-Tetraacetoxy-4(20),11-taxadiene; 2α,5,10β,14β-Tetraacetoxy-4(20),11-taxadiene-9α-ol; 2α,5,10β,14β-Tetraacetoxy-4(20),11-taxadien-9α-ol; 9α-Hydroxy-2α,5,10β,14β-tetraacetoxy-4(20),11-taxadiene; A derivative of Taxinine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our high-purity 8,8a-Bis(acetyloxy)-2a-[(acetyloxy)methyl]-1,1a,1b,1c,2a,3,3a,6a,6b,7,8,8a-dodecahydro-3,3a,6b-trihydroxy-1,1,5,7-tetramethyl-4H-cyclopropa[5',6']benz[1',2':7,8]azuleno[5,6-b]oxiren-4-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.