Description

(-)-Isocaryophyllene is a high-purity, naturally occurring sesquiterpene, a key isomer of β-caryophyllene. This compound is valued for its distinct stereochemistry and high volatility, making it a crucial chiral building block and aroma component in advanced chemical synthesis. It is primarily sought by manufacturers in the fragrance, flavor, and pharmaceutical industries for creating sophisticated scent profiles and bioactive intermediates.

Application

• Fragrance & Flavor Industry: A key chiral ingredient for creating complex, naturalistic woody, spicy, and peppery notes in premium perfumes, cosmetics, and food flavorings.
• Pharmaceutical Intermediates: Serves as a chiral starting material or synthon for the research and development of novel therapeutic agents.
• Aromatherapy & Essential Oils: Used as a high-value component in therapeutic-grade essential oil blends and natural wellness products.
• Chemical Research & Synthesis: Employed as a standard or reagent in organic chemistry research, particularly in studies involving terpene chemistry and stereoselective reactions.
• Advanced Material Science: Investigated as a precursor for bio-based polymers and sustainable specialty chemicals.

Basic Information

Product Name	(-)-Isocaryophyllene
CAS No.	118-65-0
Molecular Formula	C15H24
Molecular Weight	204.35 g/mol
Synonyms	(-)-β-Caryophyllene; (1R,4E,9S)-4,11,11-Trimethyl-8-methylenebicyclo[7.2.0]undec-4-ene; Isocaryophyllene; [1R-(1R*,4E,9S*)]-4,11,11-Trimethyl-8-methylenebicyclo[7.2.0]undec-4-ene; L-Isocaryophyllene; trans-(-)-Caryophyllene
EINECS	204-273-3

Quality Control

Our (-)-Isocaryophyllene is produced and tested under a strict quality management system. We provide material that meets high-purity standards suitable for research and industrial applications. Comprehensive analytical testing, including chiral purity assessment by GC and/or HPLC, is performed. A Certificate of Analysis (COA) detailing identity, purity, and specific rotation is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential changes in concentration.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 95.0%
Chiral Purity ([α]D)	Contact for details
Specific Rotation	Contact for details
Refractive Index (n20D)	~1.498 - 1.502
Relative Density (20°C)	~0.905 - 0.915

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.