Description

(3aS,4S,5S,6E,10Z,11aR)-10-Acetoxymethyl-4-[[[(2R,3R)-2,3-dimethyloxiranyl]carbonyl]oxy]-2,3,3a,4,5,8,9,11a-octahydro-5-hydroxy-3-methylene-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester is a complex, high-purity chemical intermediate with significant relevance in advanced organic synthesis. Its intricate stereochemistry and functional groups make it a valuable building block for the research and development of novel pharmaceutical compounds. This product is essential for medicinal chemistry researchers and process development scientists in the pharmaceutical and biotechnology industries seeking to create new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly in oncology and anti-infective research.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring specific stereochemical configurations.
• Biochemical Research: May be utilized as a probe or tool compound in studying specific biological pathways and enzyme interactions.
• Academic Research: Used in university and institutional laboratories for advanced studies in synthetic organic chemistry and methodology development.
• Custom Synthesis: Acts as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	(3aS,4S,5S,6E,10Z,11aR)-10-Acetoxymethyl-4-[[[(2R,3R)-2,3-dimethyloxiranyl]carbonyl]oxy]-2,3,3a,4,5,8,9,11a-octahydro-5-hydroxy-3-methylene-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester
CAS No.	72943-99-8
Molecular Formula	C24H32O10
Molecular Weight	480.51 g/mol
Synonyms	Methyl (3aS,4S,5S,6E,10Z,11aR)-10-(Acetoxymethyl)-4-({[(2R,3R)-2,3-dimethyloxiran-2-yl]carbonyl}oxy)-5-hydroxy-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-6-carboxylate; CAS 72943-99-8; A complex furanone epoxide derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are provided and can be tailored to meet specific client requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.