Description

(3R)-3α-Ethenyl-2,3,4A,5,6,6Aα,7,9,9A,9Bα-Decahydro-3,4Aβ,7,7,9Aβ-Pentamethylcyclopenta[F][1]Benzopyran-8(1H)-One is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate and a valuable scaffold in organic synthesis and pharmaceutical research. It is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require structurally precise building blocks for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex drug candidates, particularly in anti-inflammatory and anticancer research.
• Agrochemical Synthesis: Used in the development of novel, high-performance active ingredients with specific biological activity.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring a specific sesquiterpene backbone.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in organic chemistry and total synthesis projects.
• Material Science Research: Potential monomer or modifier for creating polymers with unique properties derived from its rigid, polycyclic structure.

Basic Information

Product Name	(3R)-3α-Ethenyl-2,3,4A,5,6,6Aα,7,9,9A,9Bα-Decahydro-3,4Aβ,7,7,9Aβ-Pentamethylcyclopenta[F][1]Benzopyran-8(1H)-One
CAS No.	1757-94-4
Molecular Formula	C20H30O2
Molecular Weight	302.45 g/mol
Synonyms	(3R)-3α-Ethenyldecahydro-3,4aβ,7,7,9aβ-pentamethylcyclopenta[f][1]benzopyran-8(1H)-one; 3α-Vinyl-3,4aβ,7,7,9aβ-pentamethyldodecahydrocyclopenta[f][1]benzopyran-8-one; (3R,4aS,6aS,9aS,9bR)-3-Ethenyl-3,4a,5,6,6a,7,9,9a,9b-decahydro-4a,7,7,9a-tetramethylnaphtho[1,2-c]furan-1(3H)-one; A structural isomer of Vetivazulene precursor.
EINECS	Contact for details

Quality Control

Our (3R)-3α-Ethenyl-2,3,4A,5,6,6Aα,7,9,9A,9Bα-Decahydro-3,4Aβ,7,7,9Aβ-Pentamethylcyclopenta[F][1]Benzopyran-8(1H)-One is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, strength, and compositional integrity. A detailed Certificate of Analysis (COA) documenting purity (typically ≥95% by HPLC), chiral excess, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.