Description

(3S)-3Aβ,4,5,6,6Aβ,9Bα-Hexahydro-3,6,9-Trimethyl-6β-Hydroxyazuleno[4,5-B]Furan-2,8(3H,7H)-Dione is a complex, high-purity sesquiterpene lactone derivative, recognized for its unique azulene-fused furanone structure. This compound is valued in advanced chemical synthesis and research for its potential as a key chiral intermediate or a scaffold for developing novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in organic and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of complex drug candidates and natural product analogs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Organic Synthesis: Employed in advanced synthetic methodologies, including cyclization and functionalization reactions, due to its reactive lactone and ketone groups.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and compound identification.
• Academic Research: Applied in university and institutional research projects focusing on novel organic reactions and natural product synthesis.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals with specific optical activity.

Basic Information

Product Name	(3S)-3Aβ,4,5,6,6Aβ,9Bα-Hexahydro-3,6,9-Trimethyl-6β-Hydroxyazuleno[4,5-B]Furan-2,8(3H,7H)-Dione
CAS No.	1618-98-0
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	6β-Hydroxy-3,6,9-trimethyl-3aβ,4,5,6,6aβ,9bα-hexahydroazuleno[4,5-b]furan-2,8-dione; 6β-Hydroxy-3,6,9-trimethyl-3aβ,4,5,6,6aβ,9bα-hexahydro-2H-azuleno[4,5-b]furan-2,8-dione; 3,6,9-Trimethyl-6β-hydroxy-3aβ,4,5,6,6aβ,9bα-hexahydroazuleno[4,5-b]furan-2,8-dione; Azuleno[4,5-b]furan-2,8-dione derivative; Sesquiterpene lactone derivative; CAS 1618-98-0.
EINECS	Contact for details

Quality Control

Our (3S)-3Aβ,4,5,6,6Aβ,9Bα-Hexahydro-3,6,9-Trimethyl-6β-Hydroxyazuleno[4,5-B]Furan-2,8(3H,7H)-Dione is produced and handled under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (IR, NMR), to ensure it meets the exacting standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.