Description

L-Threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(O-2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1→2)-O-3,4,6-tri-O-acetyl-α-D-mannopyranosyl-(1→2)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl)- is a sophisticated, high-purity synthetic building block designed for advanced research and development. This compound serves as a critical intermediate in the synthesis of complex glycopeptides and glycoproteins, enabling precise structural studies and therapeutic development. It is essential for pharmaceutical researchers, biochemists, and process development scientists working in glycobiology, drug discovery, and peptide-based therapeutic applications.

Application

• Glycopeptide Synthesis: A key protected intermediate for the solid-phase or solution-phase synthesis of complex, mannose-containing glycopeptides.
• Pharmaceutical Research: Used in the development of novel peptide-based drugs, vaccines, and diagnostic agents that require specific glycosylation patterns.
• Biochemical Studies: Enables research into protein-glycan interactions, enzyme mechanisms, and the role of specific glycosylation in biological function.
• Process Development: Serves as a reference standard or starting material for scaling up the production of therapeutic glycoproteins.
• Academic Research: A valuable tool for universities and research institutes investigating carbohydrate chemistry and chemical biology.

Basic Information

Product Name	L-Threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(O-2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1→2)-O-3,4,6-tri-O-acetyl-α-D-mannopyranosyl-(1→2)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl)-
CAS No.	482576-74-9
Molecular Formula	C71H85NO34
Molecular Weight	1496.42 g/mol
Synonyms	Fmoc-Thr[α-D-Manp-(1→2)-α-D-Manp-(1→2)-α-D-Manp(Ac)3]-OH (Peracetylated); Fmoc-L-Threonine-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1→2)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl-(1→2)-3,4,6-tri-O-acetyl-α-D-mannopyranoside); Fmoc-Thr(Ac3Man-α(1-2)Ac3Man-α(1-2)Ac3Man-α)-OH; Glycosylated Fmoc-Threonine Building Block; Protected Glycoamino Acid; Mannose Trisaccharide-Threonine Conjugate.
EINECS	Contact for details

Quality Control

This high-value building block is produced under strict quality control protocols to ensure batch-to-batch consistency and structural integrity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your critical R&D and cGMP development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.